Few seats are expected to change hands in South Australia at Saturday's election and much focus has been on Boothby, which is held by retiring Liberal MP Nicolle Flint on a 1.4 per cent margin.
The seat is likely to be a battle between Liberal candidate Rachel Swift, Labor's Louise Miller-Frost and Ms Dyer, who has been endorsed by the grassroots "Voices of" campaign and is running on a platform of greater climate action, the push for a federal integrity commission and better treatment of women.
Speaking outside a polling booth in the electorate, Ms Dyer said it would be a "hard ask" for her to claim the seat.
"What we've been trying to do with our campaign is to really have an impact on the way that the broader campaign has run and the sorts of issues that have been discussed, and the sorts of solutions that are being canvassed," she told Sky News.
"We think that by that benchmark we've certainly had a very successful campaign, but (it's) probably too tall a mountain for us to climb tonight to be able to claim victory at the end of the day."
While downplaying her own chances, Ms Dyer said there was a sense voters wanted change in the seat, which includes the suburbs of Sturt, Marion, Ascot Park, Eden Hills and Torrens Park.
"I do detect in the electorate here, and certainly nationally, there is a mood for change and I think that mood for change is warranted."
Labor is increasingly confident of winning Boothby and also has its sights on snaring Liberal-held Sturt in Adelaide's east.
