Kelce, who has found global fame as the boyfriend of Taylor Swift, will star in the upcoming series Grotesquerie by super-producer Ryan Murphy.
He will star opposite Niecy Nash-Betts, Courtney B Vance and British star Lesley Manville in the new horror drama, due to be released later this year.
Nash-Betts shared a video on Instagram in which she says: "Guys, guess who I am working with on Grotesquerie ..."
Kansas City Chiefs NFL star Travis Kelce has found global fame as the boyfriend of Taylor Swift. (AP PHOTO)
Kelce then appears in the frame and says: "Stepping into new territory with Niecy."
She captioned the video: "This is what happens when winners link up!!? @killatrav Welcome to Grostequerie!"
Nash-Betts recently won an Emmy for another Murphy series, Dahmer - Monster: The Jeffrey Dahmer Story, while Kelce won a third Super Bowl with the Kansas City Chiefs earlier this year.
Kelce has continued making a foray into Hollywood since embarking on his high-profile relationship with Swift.
He hosted the US sketch show Saturday Night Live in March 2023, which was a test of his comedy acting chops, and previously experimented with reality TV with his dating series Catching Kelce in 2016.
He was also recently announced as the host of the quiz show Are You Smarter Than A Celebrity?
Murphy is best known as the creative powerhouse behind shows such as American Horror Story, American Crime Story, Glee, Pose, Nip/Tuck and Dahmer.
He has become well known for casting high-profile stars who are not actors in his shows, giving parts in American Horror Story to singers Lady Gaga and Stevie Nicks, model Naomi Campbell and reality star Kim Kardashian.
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